Články výzkumníků z IKEM, FGÚ, ÚOCHB,UK a MUNI vzniklé s podporou projektu CarDia
2022
Jakub Křístek, Eva Sticová, Jaroslav Chlupáč, Helena Čermáková, Jana Malušková, Libor Janoušek, Michael Olausson, Jiří Froněk
Zenodo
2022
Michal Dubsky Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czechia ; Jitka Husákova; Robert Bem; Alexandra Jirkovska; Andrea Němcová; Vladimíra Fejfarova; Karol Sutoris; Michal Kahle; Edward B. Jude
Zenodo
2022
Petr Kala; Olga Gawrys; Matúš Miklovič; Zdenka Vanourková; Petra Skaroupkov; Šárka Jíchová; Janusz Sadowski; Elzbieta Kompanowska-Jezierska; Agnieszka Walkowska; Josef Veselka; Miloš Táborský; Hana Maxová; Ivana Vanecková; Ludek Cervenka
Zenodo
2022
Jiri Kanta; Anna Zavadakova; Eva Sticova; Michal Dubsky;
Zenodo
2022
Jakub Kristek; Liza Johannesson; Matthew Paul Clemons; Dana Kautznerova; Jaroslav Chlupac; Jiri Fronek; Giuliano Testa; Gregory dePrisco;
Zenodo
2022
Zdenek Matloch; Milos Mraz; Barbora Judita Kasperova; Helena Kratochvilova; Petr Svoboda; Iveta Pleyerova; Katerina Reznickova; Sarah Norman; Daniel Hlavacek; Jakub Mahrik; Peter Ivak; Zdenka Lacinova; Ivan Netuka; Martin Haluzik;
Zenodo
2022
Libor Vítek; Alena Jirásková; Ivana Malíková; Gabriela Dostálová; Lenka Eremiášová; Vilém Danzig; Aleš Linhart; Martin Haluzík;
Zenodo
2022
A Walkowska; O Gawrys; L Cervenka; E Kompanowska-Jezierska;
Zenodo
2022
Hana Bunzen; Daniel Jirák;
Zenodo
2022
Vyshakh M. Panakkal; Dominik Havlicek; Ewa Pavlova; Marcela Filipová; Semira Bener; Daniel Jirak; Ondrej Sedlacek;
zenodo
Šilhavý, J., Mlejnek, P., Šimáková, M., Liška, F., Kubovčiak, J., Sticová, E., Pravenec, M. Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension. Biomedicines. 2022, 10(2), 376
Kudová, E., Mareš, P., Hill, M., Vondráková, K., Tsenov, G., Chodounská, H., Kubová, H., Valeš, K. The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains. Pharmaceuticals. 2022, 15(1), 49
Pravenec, M., Šilhavý, J., Mlejnek, P., Šimáková, M., Mráček, T., Pecinová, A., Tauchmannová, K., Hüttl, M., Malínská, H., Kazdová, L., Neckář, J., Kolář, F., Žurmanová, J., Novotný, J., Houštěk, J. Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat. Physiological Research. 2021, 70(Suppl.4), S471-S481
Mráziková, L., Neprašová, B., Mengr, A., Popelová, A., Strnadová, V., Holá, L., Železná, B., Kuneš, J., Maletínská, L. Lipidized Prolactin-Releasing Peptide as a New Potential Tool to Treat Obesity and Type 2 Diabetes Mellitus: Preclinical Studies in Rodent Models. Frontiers in Pharmacology. 2021, 12(Nov 18), 779962
Hüttl, M., Marková, I., Miklánková, D., Zapletalová, I., Poruba, M., Haluzík, M., Vaněčková, I., Malínská, H. In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia. International Journal of Molecular Sciences. 2021, 22(21), 11513
Hojná, S., Rauchová, H., Malínská, H., Marková, I., Hüttl, M., Papoušek, F., Behuliak, M., Miklánková, D., Vaňourková, Z., Neckář, J., Kadlecová, M., Kujal, P., Zicha, J., Vaněčková, I. Antihypertensive and metabolic effects of empagliflozin in Ren-2 transgenic rats, an experimental non-diabetic model of hypertension. Biomedicine & Pharmacotherapy. 2021, 144(Dec), 112246
Dolejší, E., Szánti-Pintér, E., Chetverikov, N., Nelic, D., Randáková, A., Doležal, V., Kudová, E., Jakubík, J. Neurosteroids and steroid hormones are allosteric modulators of muscarinic receptor. Neuropharmacology. 2021, 199(Nov 1), 108798
Mengr, A., Hrubá, L., Exnerová, A., Holubová, M., Popelová, A., Železná, B., Kuneš, J., Maletínská, L. Palmitoylated Prolactin-releasing Peptide Reduced A? Plaques and Microgliosis in the Cerebellum: APP/PS1 Mice Study. Current Alzheimer Research. 2021, 18(8), 607-622
Neckář, J., Alánová, P., Olejníčková, V., Papoušek, F., Hejnová, L., Šilhavý, J., Behuliak, M., Bencze, M., Hrdlička, J., Vecka, M., Jarkovská, D., Švíglerová, J., Mistrová, E., Štengl, M., Novotný, J., Ošťádal, B., Pravenec, M., Kolář, F. Excess ischemic tachyarrhythmias trigger protection infarction in rats. Clinical science. 2021, 135(17), 2143-2163
Pirník, Z., Kořínková, L., Osacká, J., Železná, B., Kuneš, J., Maletínská, L.. Cholecystokinin System Is Involved in the Anorexigenic Effect of Peripherally Applied Palmitoylated Prolactin-Releasing Peptide in Fasted Mice. Physiological Research. 2021, 70(4), 579-590.
Karnošová, A., Strnadová, V., Holá, L., Železná, B., Kuneš, J., Maletínská, L.. Palmitoylation of Prolactin-Releasing Peptide Increased Affinity for and Activation of the GPR10, NPFF-R2 and NPFF-R1 Receptors: In Vitro Study. International Journal of Molecular Sciences. 2021, 22(16), 8904.
Dolejší, E., Chetverikov, N., Szánti-Pintér, E., Nelic, D., Randáková, A., Doležal, V., El-Fakahany, E. E., Kudová, E., Jakubík, J. Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors. Biochemical Pharmacology. 2021, 192(Oct), 114699
Holubová, K., Chvojková, M., Hrčka Krausová, B., Vyklický, V., Kudová, E., Chodounská, H., Vyklický ml., L., Valeš, K. Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia. Biomolecules. 2021, 11(7), 1026.
Kacířová, M., Železná, B., Blažková, M., Holubová, M., Popelová, A., Kuneš, J., Šedivá, B., Maletínská, L.. Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22. Journal of Neuroinflammation. 2021, 18(1), 141.
Boušová, K., Bednárová, L., Zouharová, M., Vetýšková, V., Poštulková, K., Hofbauerová, K., Petrvalská, O., Vaněk, O., Tripsianes, K., Vondrášek, J. The order of PDZ3 and TrpCage in fusion chimeras determines their properties—a biophysical characterization. Protein Science. 2021, 30(8), 1653-1666.
Husková, Z., Kikerlová, S., Sadowski, J., Alánová, P., Sedláková, L., Papoušek, F., Neckář, J. Increased Endogenous Activity of the Renin-Angiotensin System Reduces Infarct Size in the Rats with Early Angiotensin II-dependent Hypertension which Survive the Acute Ischemia/Reperfusion Injury. Frontiers in Pharmacology. 2021, 12(May 28), 679060.
Smejkalová, T., Kořínek, M., Krůšek, J., Hrčka Krausová, B., Candelas Serra, M., Hajduković, D., Kudová, E., Chodounská, H., Vyklický ml., L. Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms. British Journal of Pharmacology. 2021, 178(19), 3888-3904
Junková, K., Mirchi, L. F., Chylíková, B., Janků, M., Šilhavý, J., Hüttl, M., Marková, I., Miklánková, D., Včelák, J., Malínská, H., Pravenec, M., Šeda, O., Liška, F. Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation. Nutrients. 2021, 13(5), 1462.
Uchytilová, E., Špicarová, D., Paleček, J. Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist. International Journal of Molecular Sciences. 2021, 22(7), 3712.
Pražienková, V., Funda, J., Pirník, Z., Karnošová, A., Hrubá, L., Kořínková, L., Neprašová, B., Janovská, P., Bencze, M., Kadlecová, M., Blahoš, J., Kopecký, J., Železná, B., Kuneš, J., Bardová, K., Maletínská, L. GPR10 gene deletion in mice increases basal neuronal activity, disturbs insulin sensitivity and alters lipid homeostasis. Gene. 2021, 774(Mar 30), 145427
Hubálková, P., Ladislav, M., Vyklický, V., Smejkalová, T., Hrčka Krausová, B., Kysilov, B., Krůšek, J., Naimová, Ž., Kořínek, M., Chodounská, H., Kudová, E., Černý, J., Vyklický ml., L. Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity. Journal of Neuroscience. 2021, 41(10), 2119-2134.
Krausová, A., Burešová, P., Sarnová, L., Oyman-Eyrilmez, G., Škarda, J., Wohl, P., Bajer, L., Sticová, E., Bartoňová, L., Pácha, J., Koubková, G., Procházka, J., Sporrer, M., Durrbeck, C., Stehlíková, Zuzana, V., M., Ziolkowska, N., Sedláček, R., Jirák, D., Kverka, M., Wiche, G., Fabry, B., Kořínek, V., Gregor, M. Plectin ensures intestinal epithelial integrity and protects colon against colitis. Mucosal Immunology. 2021, 14(3), 691-702.
Filová, E., Steinerová, M., Trávníčková, M., Knitlová, J., Musílková, J., Eckhardt, A., Hadraba, D., Matějka, R., Pražák, Š., Štěpanovská, J., Kučerová, J., Riedel, T., Brynda, E., Lodererová, A., Honsová, E., Pirk, J., Koňařík, M., Bačáková, L. Accelerated in vitro recellularization of decellularized porcine pericardium for cardiovascular grafts. Biomedical Materials. 2021, 16(2), 025024.
Honetschlagerová, Z., Gawrys, O., Jíchová, Š., Škaroupková, P., Kikerlová, S., Vaňourková, Z., Husková, Z., Melenovský, V., Kompanowska., Jezierska, E., Sadowski, J., Kolář, F., Novotný, J., Hejnová, L., Kujal, P., Červenka, L. Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula. Kidney & Blood Pressure Research. 2021, 46(1), 95-113.
Ošťádal, B., Ošťádalová, I., Szárszoi, O., Netuka, I., Olejníčková, V., Hlaváčková, M. Sex-dependent effect of perinatal hypoxia on cardiac tolerance to oxygen deprivation in adults. Canadian Journal of Physiology and Pharmacology. 2021, 99(1), 1-8.
Brejchová, K., Radner, F. P. W., Balas, L., Palůchová, V., Čajka, T., Chodounská, H., Kudová, E., Schratter, M., Schreiber, R., Durand, T., Zechner, R., Kuda, O. Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides. Proceedings of the National Academy of Sciences of the United States of America. 2021, 118(2), e2020999118.
Bardová, K., Funda, J., Pohl, R., Čajka, T., Hensler, M., Kuda, O., Janovská, P., Adamcová, K., Irodenko, I., Leňková, L., Zouhar, P., Horáková, O., Flachs, P., Rossmeisl, M., Colca, J., Kopecký, J. Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue. Nutrients. 2020, 12(12), 3737.
Šilhavý, J., Malínská, H., Hüttl, M., Marková, I., Oliyarnyk, O., Mlejnek, P., Šimáková, M., Liška, F., Kazdová, L., Moravcová, R., Novotný, J., Pravenec, M. Downregulation of the Glo1 Gene Is Associated with Reduced Adiposity and Ectopic Fat Accumulation in Spontaneously Hypertensive Rats. ANTIOXIDANTS. 2020, 9(12), 1179.
Kořínková, L., Pražienková, V., Černá, L., Karnošová, A., Železná, B., Kuneš, J., Maletínská, L. Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides. Frontiers in Endocrinology. 2020, 11(Nov 26), 597583.
Pavlišová, J., Horáková, O., Kalendová, V., Burešová, J., Bardová, K., Holendová, B., Plecitá-Hlavatá, L., Vacková, Š., Windrichová, J., Topolčan, O., Kopecký, J., Rossmeisl, M. Chronic n-3 fatty acid intake enhances insulin response to oral glucose and elevates GLP-1 in high-fat diet-fed obese mice. Food & Function. 2020, 11(11), 9764-9775.
Janovská, P., Melenovský, V., Svobodová, M., Havlenová, T., Kratochvílová, H., Haluzík, M., Hošková, E., Pelikánová, T., Kautzner, J., Monzo, L., Jurcová, I., Adamcová, K., Leňková, L., Burešová, J., Rossmeisl, M., Kuda, O., Čajka, T., Kopecký, J. Dysregulation of epicardial adipose tissue in cachexia due to heart failure: the role of natriuretic peptides and cardiolipin. Journal of Cachexia Sarcopenia and Muscle. 2020, 11(6), 1614-1627.
Kosek, V., Heczková, M., Novák, F., Meisnerová, E., Nováková, O., Zelenka, J., Bechyňská, K., Vrzáčová, N., Suttnar, J., Hlaváčková, A., Danková, H., Bratová, M., Dasková, N., Malínská, H., Oliyarnyk, O., Wohl, P., Bastová, H., Hajslová, J., Cahová, M. The omega-3 Polyunsaturated Fatty Acids and Oxidative Stress in Long-Term Parenteral Nutrition Dependent Adult Patients: Functional Lipidomics Approach. Nutrients. 2020, 12(8), 2351.
Zmeškalová, A., Popelová, A., Exnerová, A., Železná, B., Kuneš, J., Maletínská, L. Cellular Signaling and Anti-Apoptotic Effects of Prolactin-Releasing Peptide and Its Analog on SH-SY5Y Cells. International Journal of Molecular Sciences. 2020, 21(17), 6343.
Matějka, R., Koňařík, M., Štěpanovská, J., Lipenský, J., Chlupáč, J., Turek, D., Pražák, Š., Brož, A., Šimůnková, Z., Mrázová, I., Forostyak, S., Kneppo, P., Rosina, J., Bačáková, L., Pirk, J. Bioreactor Processed Stromal Cell Seeding and Cultivation on Decellularized Pericardium Patches for Cardiovascular Use. Applied Sciences-Basel. 2020, 10(16), 5473.
Hrčka Krausová, B., Kysilov, B., Černý, J., Vyklický, V., Smejkalová, T., Ladislav, M., Balík, A., Kořínek, M., Chodounská, H., Kudová, E., Vyklický ml., L. Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor. Journal of Neuroscience. 2020, 40(31), 5922-5936.
Sivčev, S., Slavíková, B., Ivetic, M., Knězů, M., Kudová, E., Zemková, H. Lithocholic acid inhibits P2X2 and potentiates P2X4 receptor channel gating. Journal of Steroid Biochemistry and Molecular Biology. 2020, 202(Sep), 105725.
Mareš, P., Kudová, E., Valeš, K., Kubová, H. Three neurosteroids as well as GABAergic drugs do not convert immediate postictal potentiation to depression in immature rats. Pharmacological Reports. 2020, 72(6), 1573-1578.
Smolková, K., Špačková, J., Gotvaldová, K., Dvořák, A., Křenková, A., Hubálek, M., Holendová, B., Vítek, L., Ježek, P. SIRT3 and GCN5L regulation of NADP plus, and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2. Scientific Reports. 2020, 10(1), 8677.
Chvojková, M., Rambousek, L., Chodounská, H., Kudová, E., Valeš, K. Synthetic structural modifications of neurosteroid pregnanolone sulfate: Assessment of neuroprotective effects in vivo. European Journal of Pharmacology. 2020, 881(Aug 15), 173187.
Strnad, Š., Pražienková, V., Holubová, M., Sýkora, D., Cvačka, J., Maletínská, L., Železná, B., Kuneš, J., Vrkoslav, V. Mass spectrometry imaging of free-floating brain sections detects pathological lipid distribution in a mouse model of Alzheimer's-like pathology. Analyst. 2020, 145(13), 4595-4605.
Plecitá-Hlavatá, L., Jabůrek, M., Holendová, B., Tauber, J., Pavluch, V., Berková, Z., Cahová, M., Schröder, K., Brandes, R. P., Siemen, D., Ježek, P. Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4. Diabetes. 2020, 69(7), 1341-1354.
Kubánek, M., Schimerová, T., Piherová, L., Brodehl, A., Krebsová, A., Ratnavadivel, S., Stanasiuk, C., Hansíková, H., Zeman, J., Paleček, T., Houštěk, J., Drahota, Z., Nůsková, H., Mikešová, J., Zámečník, J., Macek, M. Jr., Ridzoň, P., Malusková, J., Stránecký, V., Melenovský, V., Milting, H., Kmoch, S. Desminopathy: Novel desmin variants, a new cardiac phenotype, and further evidence for secondary mitochondrial dysfunction. Journal of Clinical Medicine. 2020, 9(4):E937.
Filová, E., Staňková, Ľ., Eckhardt, A., Svobodová, J., Musílková, J., Pala, J., Hadraba, D., Brynda, E., Koňařík, M., Pirk, J., Bačáková, L. Modification of Human Pericardium by Chemical Crosslinking. Physiological Research. 2020, 69(1), 49-59.
Kacířová, M., Zmeškalová, A., Kořínková, L., Železná, B., Kuneš, J., Maletínská, L. Inflammation: major denominator of obesity, Type 2 diabetes and Alzheimer's disease-like pathology? Clinical science. 2020, 134(5), 547-570.
Kořínková, L., Holubová, M., Neprašová, B., Hrubá, L., Pražienková, V., Bencze, M., Haluzík, M., Kuneš, J., Maletínská, L., Železná, B. Synergistic effect of leptin and lipidized PrRP on metabolic pathways in ob/ob mice. Journal of Molecular Endocrinology. 2020, 64(2), 77-90.
Palůchová, V., Oseeva, M., Březinová, M., Čajka, T., Bardová, K., Adamcová, K., Žáček, P., Brejchová, K., Balas, L., Chodounská, H., Kudová, E., Schreiber, R., Zechner, R., Durand, T., Rossmeisl, M., Abumrad, N. A., Kopecký, J., Kuda, O. Lipokine 5-PAHSA is regulated by adipose triglyceride lipase and primes adipocytes for de novo lipogenesis in mice. Diabetes. 2020, 69(3), 300-312.
Sládek, M., Röschová, M., Adámková, V., Hamplová, D., Sumová, A. Chronotype assessment via a large scale socio-demographic survey favours yearlong Standard time over Daylight Saving Time in central Europe. Scientific Reports. 2020, 10(1), 1419.
Musílková, J., Filová, E., Pala, J., Matějka, R., Hadraba, D., Vondrášek, D., Kaplan, O., Riedel, T., Brynda, E., Kučerová, J., Koňařík, M., Lopot, F., Pirk, J., Bačáková, L. Human decellularized and crosslinked pericardium coated with bioactive molecular assemblies. Biomedical Materials. 2019, 15(1), 015008.
Pšenáková, K., Hexnerová, R., Srb, P., Obšilová, V., Veverka, V., Obšil, T. The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress. FEBS Journal. 2019, 287(8), 1626), 1644.
Tomášová, P., Bugáňová, M., Pelantová, H., Holubová, M., Šedivá, B., Železná, B., Haluzík, M., Maletínská, L., Kuneš, J., Kuzma, M. Metabolomics Based on MS in Mice with Diet-Induced Obesity and Type 2 Diabetes Mellitus: the Effect of Vildagliptin, Metformin, and Their Combination. Applied Biochemistry and Biotechnology. 2019, 188(1), 165-184.
Holubová, M., Hrubá, L., Popelová, A., Bencze, M., Pražienková, V., Gengler, S., Kratochvílová, H., Haluzík, M., Železná, B., Kuneš, J., Hölscher, C., Maletínská, L. Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of beta-amyloid pathology. Neuropharmacology. 2019, 144(Jan), 377-387.
Čermáková, M., Pelantová, H., Neprašová, B., Šedivá, B., Maletínská, L., Kuneš, J., Tomášová, P., Železná, B., Kuzma, M. Metabolomic Study of Obesity and Its Treatment with Palmitoylated Prolactin-Releasing Peptide Analog in Spontaneously Hypertensive and Normotensive Rats. Journal of Proteome Research. 2019, 18(4), 1735-1750.
Maletínská, L., Popelová, A., Železná, B., Bencze, M., Kuneš, J. The impact of anorexigenic peptides in experimental models of Alzheimer's disease pathology. Journal of Endocrinology. 2019, 240(2), R47-R72.
Pražienková, V., Schirmer, C., Holubová, M., Železná, B., Kuneš, J., Galas, M. C., Maletínská, L. Lipidized Prolactin-Releasing Peptide Agonist Attenuates Hypothermia-Induced Tau Hyperphosphorylation in Neurons. Journal of Alzheimer's Disease. 2019, 67(4), 1187-1200.
Pražienková, V., Popelová, A., Kuneš, J., Maletínská, L. Prolactin-Releasing Peptide: Physiological and Pharmacological Properties. International Journal of Molecular Sciences. 2019, 20(21), 5297.
Pšenáková, K., Kohoutová, K., Obšilová, V., Ausserlechner, M. J., Veverka, V., Obšil, T. Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics. Cells. 2019, 8(9), 966.
Sivčev, S., Slavíková, B., Rupert, M., Ivetic, M., Nekardová, M., Kudová, E., Zemková, H. Synthetic testosterone derivatives modulate rat P2X2 and P2X4 receptor channel gating. Journal of Neurochemistry. 2019, 150(1), 28-43.
Šmídová, A., Staňková, K., Petrvalská, O., Lazar, J., Sychrová, H., Obšil, T., Zimmermannová, O., Obšilová, V. The activity of Saccharomyces cerevisiae Na+, K+/H+ antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481. Biochimica Et Biophysica Acta-Molecular Cell Research. 2019, 1866(12), 118534.
Šoltésová, M., Elicharová, H., Srb, P., Růžička, M., Janisova, L., Sychrová, H., Lang, J. Nuclear magnetic resonance investigation of water transport through the plasma membrane of various yeast species. FEMS Microbiology Letters. 2019, 366(18), fnz220.
Beyrand, V., Voeten, D. F. A. E., Bureš, S., Fernandez, V., Janáček, J., Jirák, D., Rauhut, O., Tafforeau, P. Multiphase progenetic development shaped the brain of flying archosaurs. Scientific Reports. 2019, 9(Jul 25), 10807.
Čertíková ,- Chábová, V., Kujal, P., Vaňourková, Z., Škaroupková, P., Sadowski, J., Kompanowska ,, Jezierska, E., Tesař, V., Hammock, B., Imig, J., Maxová, H., Červenka, L., Vaněčková, I. Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats. Kidney & Blood Pressure Research. 2019, 44(6), 1493-1505.
Hrdlička, J., Neckář, J., Papoušek, F., Husková, Z., Kikerlová, S., Vaňourková, Z., Vernerová, Z., Akat, F., Vašinová, J., Hammock, B.D., Hwang, S.H., Imig, J. D., Falck, J. R., Červenka, L., Kolář, F. Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats. Frontiers in Pharmacology. 2019, 10(Mar 1), 159.
Janáček, J., Jirák, D. Volume tensor estimation using a virtual line grid: study of a developing pheasant brain. Image Analysis and Stereology. 2019, 38(3), 255-260.
Janáček, J., Jirák, D. Variance of the isotropic uniform systematic sampling. Image Analysis and Stereology. 2019, 38(3), 261-267.
Krátký, V., Kikerlová, S., Husková, Z., Sadowski, J., Kolář, F., Červenka, L. Enhanced Renal Vascular Responsiveness to Angiotensin II and Norepinephrine: A Unique Feature of Female Rats with Congestive Heart Failure. Kidney & Blood Pressure Research. 2019, 44(5), 1128-1141.
Neckář, J., Khan, M. A. H., Gross, G. J., Cyprová, M., Hrdlička, J., Kvasilová, A., Falck, J. R., Campbell, W. B., Sedláková, L., Škutová, Š., Olejníčková, V., Gregorovičová, M., Sedmera, D., Kolář, F., Imig, J. D. Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats. Clinical science. 2019, 133(8), 939-951.
Řezáčová, L., Hojná, S., Kopkan, L., Rauchová, H., Kadlecová, M., Zicha, J., Vaněčková, I. Role of angiotensin II in chronic blood pressure control of heterozygous Ren-2 transgenic rats: Peripheral vasoconstriction versus central sympathoexcitation. Biomedicine & Pharmacotherapy. 2019, 116(Aug), 108996.
Svoboda, P., Křížová, E., Šestáková, Š., Vápenková, K., Knejzlík, Z., Rimpelová, S., Rayová, D., Volfová, N., Křížová, I., Rumlová, M., Sýkora, D., Kizek, R., Haluzík, M., Zídek, V., Zídková, J., Škop, V. Nuclear transport of nicotinamide phosphoribosyltransferase is cell cycle-dependent in mammalian cells, and its inhibition slows cell growth. Journal of Biological Chemistry. 2019, 294(22), 8676-8689.
Vacková, Š., Kikerlová, S., Melenovský, V., Kolář, F., Imig, J. D., Kompanowska ,- Jezierska, E., Sadowski, J., Červenka, L. Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure. Kidney & Blood Pressure Research. 2019, 44(4), 792-809.
Vaněčková, I., Behuliak, M., Hojná, S., Kopkan, L., Kadlecová, M., Zicha, J. Exaggerated blood pressure response to fasudil or nifedipine in hypertensive Ren-2 transgenic rats: role of altered baroreflex. Hypertension Research. 2019, 42(2), 145-154.
Vaněčková, I., Hojná, S., Vernerová, Z., Kadlecová, M., Rauchová, H., Kompanowska ,- Jezierska, E., Vaňourková, Z., Červenka, L., Zicha, J. Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ETA Blockade. Frontiers in physiology. 2019, 10(Sep 18), 1145.
Zicha, J., Hojná, S., Kopkan, L., Červenka, L., Vaněčková, I. The Absence of Sympathoexcitation During the Development of Hypertension in Cyp1a1 Ren-2 Transgenic Rats. Physiological Research. 2019, 68(2), 329-334.
Popelová, A., Kákonová, A., Hrubá, L., Kuneš, J., Maletínská, L., Železná, B. Potential neuroprotective and anti-apoptotic properties of a long-lasting stable analog of ghrelin: an in vitro study using SH-SY5Y cells. Physiological Research. 2018, 67(2), 339-346.
Kapras, V., Vyklický, V., Buděšínský, M., Císařová, I., Vyklický ml., L., Chodounská, H., Jahn, U. Total Synthesis of ent-Pregnanolone Sulfate and Its Biological Investigation at the NMDA Receptor. Organic Letters. 2018, 20(4), 946-949.
Krausová, B., Slavíková, B., Nekardová, M., Hubálková, P., Vyklický, V., Chodounská, H., Vyklický ml., L., Kudová, E. Positive Modulators of the N-Methyl-D-aspartate Receptor: Structure-Activity Relationship Study of Steroidal 3-Hemiesters. Journal of Medicinal Chemistry. 2018, 61(10), 4505-4516.
Mikulášková, B., Holubová, M., Pražienková, V., Zemenová, J., Hrubá, L., Haluzík, M., Železná, B., Kuneš, J., Maletínská, L. Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study. Nutrition & Diabetes. 2018, 8(Jan 16), 5.
Holubová, M., Blechová, M., Kákonová, A., Kuneš, J., Železná, B., Maletínská, L. In Vitro and In Vivo Characterization of Novel Stable Peptidic Ghrelin Analogs: Beneficial Effects in the Settings of Lipopolysaccharide-Induced Anorexia in Mice. Journal of Pharmacology and Experimental Therapeutics. 2018, 366(3), 422-432.
Holubová, M., Hrubá, L., Neprašová, B., Majerčíková, Z., Lacinová, Z., Kuneš, J., Maletínská, L., Železná, B. Prolactin-releasing peptide improved leptin hypothalamic signaling in obese mice. Journal of Molecular Endocrinology. 2018, 60(2), 85-94.
Mikulášková, B., Holubová, M., Pražienková, V., Zemenová, J., Hrubá, L., Haluzík, M., Železná, B., Kuneš, J., Maletínská, L. Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study. Nutrition & Diabetes. 2018, 8(Jan 16), 5.
Adla, S. K., Slavíková, B., Chodounská, H., Vyklický, V., Ladislav, M., Hubálková, P., Krausová, B., Smejkalová, T., Nekardová, M., Šmídková, M., Monincová, L., Souček, R., Vyklický ml., L., Kudová, E. Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif. Frontiers in Pharmacology. 2018, 9(Nov 12), 1299.
Antošová, Z., Herkommerová, K., Pichová, I., Sychrová, H. Efficient secretion of three fungal laccases from Saccharomyces cerevisiae and their potential for decolorization of textile industry effluent - A comparative study. Biotechnology Progress. 2018, 34(1), 69-80.
Boušová, K., Herman, P., Večeř, J., Bednárová, L., Monincová, L., Majer, P., Vyklický ml., L., Vondrášek, J., Teisinger, J. Shared CaM- and S100A1-binding epitopes in the distal TRPM4 N terminus. FEBS Journal. 2018, 285(3), 599-613.
Herkommerová, K., Dostál, J., Pichová, I. Decolorization and detoxification of textile wastewaters by recombinant Myceliophthora thermophila and Trametes trogii laccases. 3 Biotech. 2018, 8(12), 505.
Jirátová, M., Pospíšilová, A., Rabyk, M., Pařízek, M., Kovář, J., Gálisová, A., Hrubý, M., Jirák, D. Biological characterization of a novel hybrid copolymer carrier system based on glycogen. Drug Delivery and Translational Research. 2018, 8(1), 73-82.
Popelová, A., Pražienková, V., Neprašová, B., Kasperová, B. J., Hrubá, L., Holubová, M., Zemenová, J., Blum, D., Železná, B., Galas, M. C., Kuneš, J., Maletínská, L. Novel Lipidized Analog of Prolactin-Releasing Peptide Improves Memory Impairment and Attenuates Hyperphosphorylation of Tau Protein in a Mouse Model of Tauopathy. Journal of Alzheimer's Disease. 2018, 62(4), 1725-1736.
Vyklický, V., Krausová, B., Černý, J., Ladislav, M., Smejkalová, T., Kysilov, B., Kořínek, M., Danačíková, Š., Horák, M., Chodounská, H., Kudová, E., Vyklický ml., L. Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit. Frontiers in Molecular Neuroscience. 2018, 11(Apr 6), 110.
Červenka, L., Husková, Z., Kopkan, L., Kikerlová, S., Sedláková, L., Vaňourková, Z., Alánová, P., Kolář, F., Hammock, B.D., Hwang, S.H., Imig, J. D., Falck, J. R., Sadowski, J., Kompanowska ,- Jezierska, E., Neckář, J. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. Journal of Hypertension. 2018, 36(6), 1326-1341.
Dvořák, J., Švihlík, J., Kybic, J., Radochová, B., Janáček, J., Kukal, J., Borovec, J., Habart, D. Volume estimation from single images: an application to pancreatic islets. Image Analysis and Stereology. 2018, 37(3), 191-204.
Krátký, V., Kopkan, L., Kikerlová, S., Husková, Z., Táborský, M., Sadowski, J., Kolář, F., Červenka, L. The Role of Renal Vascular Reactivity in the Development of Renal Dysfunction in Compensated and Decompensated Congestive Heart Failure. Kidney & Blood Pressure Research. 2018, 43(6), 1730-1741.
Mikulášková, B., Holubová, M., Pražienková, V., Zemenová, J., Hrubá, L., Haluzík, M., Železná, B., Kuneš, J., Maletínská, L. Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study. Nutrition & Diabetes. 2018, 8(Jan 16), 5.
Neckář, J., Hsu, A., Khan, M. A. H., Gross, G. J., Nithipatikom, K., Cyprová, M., Benák, D., Hlaváčková, M., Sotáková-Kašparová, D., Falck, J. R., Sedmera, D., Kolář, F., Imig, J. D. Infarct size-limiting effect of epoxyeicosatrienoic acid analog EET-B is mediated by hypoxia-inducible factor-1 alpha via downregulation of prolyl hydroxylase 3. American Journal of Physiology-Heart and Circulatory Physiology. 2018, 315(5), H1148-H1158.
Peševski, Ž., Kvasilová, A., Stopková, T., Naňka, O., Drobná Krejčí, E., Buffinton, C., Kočková, R., Eckhardt, A., Sedmera, D. Endocardial Fibroelastosis is Secondary to Hemodynamic Alterations in the Chick Embryonic Model of Hypoplastic Left Heart Syndrome. Developmental Dynamics. 2018, 247(3), 509-520.
Poledne, R., Zicha, J. Human genome evolution and development of cardiovascular risk factors through natural selection. Physiological Research. 2018, 67(2), 155-163.
Pravenec, M., Saba, L. M., Zídek, V., Landa, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Strnad, H., Trnovská, J., Škop, V., Hüttl, M., Marková, I., Oliyarnyk, O., Malínská, H., Kazdová, L., Smith, H., Tabakoff, B. Systems genetic analysis of brown adipose tissue function. Physiological Genomics. 2018, 50(1), 52-66.
Rossmeisl, M., Pavlišová, J., Janovská, P., Kuda, O., Bardová, K., Hansíková, J., Svobodová, M., Oseeva, M., Veleba, J., Kopecký Jr., J., Žáček, P., Fišerová, E., Pelikánová, T., Kopecký, J. Differential modulation of white adipose tissue endocannabinoid levels by n-3 fatty acids in obese mice and type 2 diabetic patients. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. 2018, 1863(7), 712-725.
Sedláková, L., Kikerlová, S., Husková, Z., Červenková, L., Čertíková ,- Chábová, V., Zicha, J., Falck, J. R., Imig, J. D., Kompanowska ,, Jezierska, E., Sadowski, J., Krátký, V., Červenka, L., Kopkan, L. 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats. Bioscience Reports. 2018, 38(5), BSR20171496.
Straka, F., Schorník, D., Mašín, J., Filová, E., Miřejovský, T., Burdíková, Z., Švindrych, Z., Chlup, H., Horný, L., Daniel, M., Machač, J., Skibová, J., Pirk, J., Bačáková, L. A human pericardium biopolymeric scaffold for autologous heart valve tissue engineering: cellular and extracellular matrix structure and biomechanical properties in comparison with a normal aortic heart valve. Journal of Biomaterial Science Polymer Edition. 2018, 29(6), 599-634.
Šilhavý, J., Krijt, J., Sokolová, J., Zídek, V., Mlejnek, P., Šimáková, M., Škop, V., Trnovská, J., Oliyarnyk, O., Marková, I., Hüttl, M., Malínská, H., Kazdová, L., Liška, F., Kožich, V., Pravenec, M. Dissecting the role of Folr1 and Folh1 genes in the pathogenesis of metabolic syndrome in spontaneously hypertensive rats. Physiological Research. 2018, 67(4), 657-662.
Šilhavý, J., Mlejnek, P., Šimáková, M., Vaněčková, I., Behuliak, M., Kuda, O., Sticová, E., Jirsa, M., Pravenec, M. Acute toxic effects of telmisartan in spontaneously hypertensive rats fed a high fructose diet. Physiological Research. 2018, 67(6), 851-856.
Vaněčková, I., Hojná, S., Kadlecová, M., Vernerová, Z., Kopkan, L., Červenka, L., Zicha, J. Renoprotective Effects of ETA Receptor Antagonists Therapy in Experimental Non-Diabetic Chronic Kidney Disease: Is There Still Hope for the Future? Physiological Research. 2018, 67(Suppl.1), S55-S67.
Bugáňová, M., Pelantová, H., Holubová, M., Šedivá, B., Maletínská, L., Železná, B., Kuneš, J., Kačer, P., Kuzma, M., Haluzík, M. The effects of liraglutide in mice with diet-induced obesity studied by metabolomics. Journal of Endocrinology. 2017, 233(1), 93-104.
Pražienková, V., Holubová, M., Pelantová, H., Bugáňová, M., Pirník, Z., Mikulášková, B., Popelová, A., Blechová, M., Haluzík, M., Železná, B., Kuzma, M., Kuneš, J., Maletínská, L. Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity. PLoS ONE. 2017, 12(8), e0183449.
Adla, S. K., Slavíková, B., Šmídková, M., Tloušťová, E., Svoboda, M., Vyklický, V., Krausová, B., Hubálková, P., Nekardová, M., Holubová, K., Valeš, K., Buděšínský, M., Vyklický ml., L., Chodounská, H., Kudová, E. Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors. Steroids. 2017, 117(Jan), 52-61.
Gibalová, A., Steinbachová, L., Hafidh, S., Bláhová, V., Gadiou, Z., Michailidis, C., Müller, K., Pleskot, R., Dupľáková, N., Honys, D. Characterization of pollen-expressed bZIP protein interactions and the role of ATbZIP18 in the male gametophyte. Plant Reproduction. 2017, 30(1), 1-17.
Kao, H. Y., Dvořák, D., Park, E., Kenney, J., Kelemen, E., Fenton, A.A. Phencyclidine Discoordinates Hippocampal Network Activity But Not Place Fields. Journal of Neuroscience. 2017, 37(49), 12031-12049.
Zemenová, J., Sýkora, D., Maletínská, L., Kuneš, J. Lipopeptides as therapeutics: applications and in vivo quantitative analysis. Bioanalysis. 2017, 9(2), 215-230.
Jirák, D., Janáček, J. Volume of the crocodilian brain and endocast during ontogeny. PLoS ONE. 2017, 12(6), e0178491.
Kostiv, U., Rajsiglová, L., Luptáková, D., Pluháček, T., Vannucci, L., Havlíček, V., Engstová, H., Jirák, D., Šlouf, M., Makovický, P., Sedláček, R., Horák, D. Biodistribution of upconversion/magnetic silica-coated NaGdF4:Yb3+/Er3+ nanoparticles in mouse models. RSC Advances. 2017, 7(73), 45997-46006.
Liška, F., Landa, V., Zídek, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Strnad, H., Trnovská, J., Škop, V., Kazdová, L., Starker, C.G., Voytas, D.F., Izsvák, Z., Mancini, M., Šeda, O., Křen, V., Pravenec, M. Downregulation of Plzf Gene Ameliorates Metabolic and Cardiac Traits in the Spontaneously Hypertensive Rat. Hypertension. 2017, 69(6), 1084-1091.
Lišková, J., Hadraba, D., Filová, E., Koňařík, M., Pirk, J., Jelen, K., Bačáková, L. Valve interstitial cell culture: Production of mature type I collagen and precise detection. Microscopy Research and Technique. 2017, 80(8), 936-942.
Melenovský, V., Petrák, J., Mráček, T., Beneš, J., Borlaug, B. A., Nůsková, H., Pluháček, T., Špatenka, J., Kovalčíková, J., Drahota, Z., Kautzner, J., Pirk, J., Houštěk, J. Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. European Journal of Heart Failure. 2017, 19(4), 522-530.
Neckář, J., Svatoňová, A., Weissová, R., Drahota, Z., Zajíčková, P., Brabcová, I., Kolář, D., Alánová, P., Vašinová, J., Šilhavý, J., Hlaváčková, M., Tauchmannová, K., Milerová, M., Ošťádal, B., Červenka, L., Žurmanová, J., Kalous, M., Nováková, O., Novotný, J., Pravenec, M., Kolář, F. Selective replacement of mitochondrial DNA increases the cardioprotective effect of chronic continuous hypoxia in spontaneously hypertensive rats. Clinical science. 2017, 131(9), 865-881.
Pravenec, M., Zídek, V., Landa, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Trnovská, J., Škop, V., Marková, I., Malínská, H., Hüttl, M., Kazdová, L., Bardová, K., Tauchmannová, K., Vrbacký, M., Nůsková, H., Mráček, T., Kopecký, J., Houštěk, J. Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity. Physiological Research. 2017, 66(6), 917-924.
Sedláková, L., Čertíková ,- Chábová, V., Doleželová, Š., Škaroupková, P., Kopkan, L., Husková, Z., Červenková, L., Kikerlová, S., Vaněčková, I., Sadowski, J., Kompanowska ,, Jezierska, E., Kujal, P., Kramer, H. J., Červenka, L. Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and Experimental Hypertension. 2017, 39(2), 183-195.
Straka, F., Schorník, D., Mašín, J., Filová, E., Miřejovský, T., Burdíková, Z., Švindrych, Z., Chlup, H., Horný, L., Veselý, J., Pirk, J., Bačáková, L. A New Approach to Heart Valve Tissue Engineering Based on Modifying Autologous Human Pericardium by 3D Cellular Mechanotransduction. Journal of Biomaterials and Tissue Engineering. 2017, 7(7), 527-543.
Šeda, O., Liška, F., Pravenec, M., Vernerová, Z., Kazdová, L., Křenová, D., Zídek, V., Šedová, L., Krupková, M., Křen, V. Connexin 50 Mutation Lowers Blood Pressure in Spontaneously Hypertensive Rat. Physiological Research. 2017, 66(1), 15-28.
Špaček, T., Pavluch, V., Alán, L., Capková, N., Engstová, H., Dlasková, A., Berková, Z., Saudek, F., Ježek, P. Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet beta-cells of diabetic Goto Kakizaki rats. Scientific Reports. 2017, 7(Nov 15), 15674.
Trnovská, J., Šilhavý, J., Kuda, O., Landa, V., Zídek, V., Mlejnek, P., Šimáková, M., Strnad, H., Škop, V., Oliyarnyk, O., Kazdová, L., Haluzík, M., Pravenec, M. Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls. PLoS ONE. 2017, 12(6), e0179063.